{"id":11455,"date":"2019-09-16T13:57:15","date_gmt":"2019-09-16T13:57:15","guid":{"rendered":"http:\/\/hunimed-new.local\/Member\/ana-lleo-de-nalda-2\/"},"modified":"2026-03-31T12:45:43","modified_gmt":"2026-03-31T12:45:43","slug":"ana-lleo-de-nalda","status":"publish","type":"member","link":"https:\/\/www.hunimed.eu\/it\/member\/ana-lleo-de-nalda\/","title":{"rendered":"Ana Lleo de Nalda"},"content":{"rendered":"\n<div class=\"wp-block-hunimed-tabs-content hunimed-tabs-content-block\"><div class=\"tabs-container\">\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Biosketch\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Biosketch<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p class=\"wp-block-paragraph\"><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2019 &#8211; 2022: <\/strong>Professore Associato di Medicina Interna, Âéw¶¹´«Ã½<\/li>\n\n\n\n<li><strong>2017 &#8211; 2019: <\/strong>Ricercatore RTDA Medicina Interna, Âéw¶¹´«Ã½<\/li>\n\n\n\n<li><strong>2006 &#8211; 2009: <\/strong>PhD in Metodologia Clinica, Universit\u00e0 degli Studi di Milano<\/li>\n\n\n\n<li><strong>2001 &#8211; 2006: <\/strong>Specializzazione in Medicina Interna, Universit\u00e0 degli Studi di Milano<\/li>\n\n\n\n<li><strong>2000:<\/strong> Laurea Medicina e Chirurgia, Universit\u00e0 degli Studi di Milano<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2025 &#8211; present:<\/strong> Vicepresidente, MEDTEC School, Âéw¶¹´«Ã½, Milan, IT<\/li>\n\n\n\n<li><strong>2025 &#8211; present: <\/strong>Collegio di Dottorato, Personalized caRe and Innovation in Medicine and Engineering (PRIME), Âéw¶¹´«Ã½ e Politecnico di Milan<\/li>\n\n\n\n<li><strong>2021 &#8211; present: <\/strong>Direttore, Scuola di Specializzazione, Âéw¶¹´«Ã½<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Premi e Onorificenze<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2025 &#8211; present: <\/strong>Vice Secretary General European Association for the Study of the Liver<\/li>\n\n\n\n<li><strong>2022  &#8211; 2025: <\/strong>Scientific Committee European Association for the Study of the Liver<\/li>\n\n\n\n<li><strong>2020 &#8211; 2023: <\/strong>Scientific Committee Italian Association of Internal Medicine, Lombardy section<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Ricerca\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Ricerca<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p class=\"wp-block-paragraph\">I principali interessi di ricerca sono volti a chiarire la&nbsp;<strong>patogenesi della colangite biliare primitiva<\/strong>&nbsp;(CBP). Ha descritto per la prima volta caratteristiche specifiche delle cellule epiteliali delle vie biliari (BEC), il bersaglio dell\u2019attacco immune nella CBP, che sembrerebbero essenziali per spiegare la specificit\u00e0 delle vie biliari di CBP, la recidiva della malattia dopo il trapianto di fegato, e il successo terapeutico dell\u2019acido ursodesossicolico.<br><br>\u00c8 membro dei Gruppi di Studio internazionali per lo studio della PBC (PBC Global Group), della Colangite Sclerosante Primitiva (International PSC Study Group) e dell\u2019Epatite Autoimmune.<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Pubblicazioni\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Pubblicazioni<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<ol class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40348684\/\">EASL Clinical Practice Guidelines on the management of autoimmune hepatitis<\/a>. J Hepatol. 2025 Aug;83(2):453-501. doi: 10.1016\/j.jhep.2025.03.017.<\/li>\n\n\n\n<li>Milardi G, Franceschini B, Camisaschi C, Puccio S, Costa G, Soldani C, Uva P, Cangelosi D, Carriero R, Lambroia L, Cammarota A, Lodetti-Zangrandi G, Malenica I, Erreni M, Montali I, Lottini T, Raggi C, Kunderfranco P, Polidoro MA, Aghemo A, Balsano R, Pressiani T, Piscuoglio S, Di Tommaso L, Torzilli G, Rimassa L, Lugli E, Cassani B, <strong>Lleo A<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40889886\/\">Immunosuppressive contribution of tumour-infiltrating B cells in human intrahepatic cholangiocarcinoma and their role in chemoimmunotherapy outcome<\/a>.<\/li>\n\n\n\n<li>Colapietro F, Maisonneuve P, Lytvyak E, Beuers U, Verdonk RC, van der Meer AJ, van Hoek B, Kuiken SD, Brouwer JT, Muratori P, Aghemo A, Carella F, van den Berg AP, Zachou K, Dalekos GN, Di Zeo-S\u00e1nchez DE, Robles M, Andrade RJ, Montano-Loza AJ, van den Brand FF, Slooter CD, Macedo G, Liberal R, de Boer YS, <strong>Lleo A<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37802188\/\">Incidence and predictors of hepatocellular carcinoma in patients with autoimmune hepatitis<\/a>. J Hepatol. 2024 Jan;80(1):53-61. doi: 10.1016\/j.jhep.2023.09.010.<\/li>\n\n\n\n<li>Alvisi G, Termanini A, Soldani C, Portale F, Carriero R, Pilipow K, Costa G, Polidoro M, Franceschini B, Malenica I, Puccio S, Lise V, Galletti G, Zanon V, Colombo FS, De Simone G, Tufano M, Aghemo A, Di Tommaso L, Peano C, Cibella J, Iannacone M, Roychoudhuri R, Manzo T, Donadon M, Torzilli G, Kunderfranco P, Di Mitri D, Lugli E, <strong>Lleo A<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35738508\/\">Multimodal single-cell profiling of intrahepatic cholangiocarcinoma defines hyperactivated Tregs as a potential therapeutic target<\/a>. J Hepatol 2022, Nov;77(5):1359-1372. doi: https:\/\/doi.org\/10.1016\/j.jhep.2022.05.043<\/li>\n\n\n\n<li><strong>Lleo A<\/strong>, Wang G-Q, Gershwin ME, Hirschfield GM. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33308474\/\">Primary biliary cholangitis<\/a>. Lancet 2020 12;396(10266):1915-1926.\u00a0 doi: 10.1016\/S0140-6736(20)31607-X.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","departaments":[251],"roles":[203],"class_list":["post-11455","member","type-member","status-publish","hentry","departament-medicina-interna","role-full-professor-it"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ana Lleo de Nalda - Hunimed<\/title>\n<meta name=\"description\" content=\"Biosketch Formazione 2019 - 2022: Professore Associato di Medicina Interna, Âéw¶¹´«Ã½ 2017 - 2019: Ricercatore RTDA Medicina Interna, Humanitas\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hunimed.eu\/it\/member\/ana-lleo-de-nalda\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ana Lleo de Nalda - 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