{"id":11472,"date":"2019-09-16T08:46:20","date_gmt":"2019-09-16T08:46:20","guid":{"rendered":"http:\/\/hunimed-new.local\/Member\/gianluigi-condorelli-2\/"},"modified":"2026-03-31T07:36:54","modified_gmt":"2026-03-31T07:36:54","slug":"gianluigi-condorelli","status":"publish","type":"member","link":"https:\/\/www.hunimed.eu\/it\/member\/gianluigi-condorelli\/","title":{"rendered":"Gianluigi Condorelli"},"content":{"rendered":"\n<div class=\"wp-block-hunimed-tabs-content hunimed-tabs-content-block\"><div class=\"tabs-container\">\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Biosketch\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Biosketch<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p class=\"wp-block-paragraph\"><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>1997<\/strong>: Specializzazione in Cardiologia presso la Seconda Universit\u00e0 di Napoli<\/li>\n\n\n\n<li><strong>1993<\/strong>: Dottorato di ricerca in Fisiopatologia cardiovascolare presso l\u2019Universit\u00e0 degli Studi Tor Vergata di Roma<\/li>\n\n\n\n<li><strong>1989:<\/strong> Laurea in Medicina e Chirurgia presso l\u2019Universit\u00e0 degli Studi Federico II di Napoli<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Coordinatore, Cardiovascular Diseases, CdL Medicina e Chirurgia<\/li>\n\n\n\n<li>Professore, Organ System Disease I, Blood Heart and Lung, MEDTEC School<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Ricerca\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Ricerca<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p class=\"wp-block-paragraph\">La mia ricerca \u00e8 incentrata sulla comprensione dei meccanismi molecolari delle malattie cardiovascolari, in particolare lo scompenso cardiaco. In quest\u2019ambito, da diversi anni studio i meccanismi che regolano la traduzione del segnale e il ruolo dell\u2019epigenetica e degli RNA non codificanti nelle funzioni del cardiomiocita, la cellula responsabile della contrattilit\u00e0 del cuore. La finalit\u00e0 \u00e8 d\u2019identificare nuove molecole che possano migliorarne la funzionalit\u00e0 in condizioni patologiche. Inoltre, utilizzo tecniche di \u201chigh throughput sequencing\u201d per identificare mutazioni alla base di forme ereditarie di cardiomiopatie primitive, generando poi cellule staminali \u201ciPCS\u201d per studiare in cardiomiociti umani queste patologie. Infine, ci occupiamo di identificare nuovi biomarker molecolari di patologie cardiovascolari nell\u2019uomo.<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Pubblicazioni\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Pubblicazioni<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<ol class=\"wp-block-list\">\n<li>Condorelli, G., Drusco, A., Stassi, G., Roncarati, R., Iaccarino, G., Russo, M.A., Gu, Y., Chung, C., Latronico, M., Napoli, C., Sadoshima, J., Croce, C.M., and Ross, J., jr. (2002): <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12237475\/\">Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice<\/a>. <strong>Natl. Acad. Sci. USA<\/strong>, 99: 12333-8<\/li>\n\n\n\n<li>Car\u00e8, A., Catalucci, D., Felicetti, F.,&nbsp;Bonci&nbsp;D., Ruiz-Lozano, P., Gallo, P., Segnalini, P., Bang, M.L., Dorn, G.W.2<sup>nd<\/sup>, Ellingsen, O., Croce, C.M., Peschle, C., and&nbsp;<strong>Condorelli<sup>&nbsp;<\/sup>G.<\/strong>(2007) \u2013&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17468766\/\">MicroRNA-133 controls cardiac myocyte hypertrophy<\/a><em>.<\/em>&nbsp;Nature Medicine, 13(5):613-8.<\/li>\n\n\n\n<li>Zhang, D.H., Latronico, M.V.G., Zhang, J.L., Contu, R., Rizzi, R., Catalucci, D., Peterson, K.L., Brown, J.H., Chen, J, Sonenberg, N. and&nbsp;<strong>Condorelli G.<\/strong>&nbsp;(2010) \u2013&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20644257\/\">MTORC-1 regulates cardiac function and myocyte survival through 4E-BP-1 inhibition in mice.<\/a> The Journal of Clinical Investigation, 120(8):2805-16<\/li>\n\n\n\n<li>Greco CM, Kunderfranco, P., Rubino, M., Larcher, V., Carullo, P., Anselmo, A., Kurz, K., Carell, T., Angius, A., Latronico, MiVG, Papait, R., and <strong>Condorelli G<\/strong> (2016) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27489048\/\">DNA Hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy<\/a> <strong>Nature Comm<\/strong>, 7:12418. doi: 10.1038\/ncomms12418<\/li>\n\n\n\n<li>Kallikourdis M, Martini E, Carullo P, Sardi C, Roselli G, Greco CM, Vignali D, Riva, F, Ormbostad Berre AM, Stolen TO, Fumero A, Faggian G, Di Pasquale E, Elia L, Rumio C, Catalucci D, Papait R, <strong>Condorelli G<\/strong>: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28262700\/\">T cell costimulation blockade blunts pressure overload-induced heart failure<\/a>: <strong>Nature Comm<\/strong>, 8:14680<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":32672,"template":"","departaments":[3469],"roles":[206],"class_list":["post-11472","member","type-member","status-publish","has-post-thumbnail","hentry","departament-malattie-dellapparato-cardiovascolare-2","role-professore-ordinario"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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